Seven-hour sleep EEG recordings were obtained from rats (N = 15) given a single acute dose, and rats (N = 15) given 14 daily doses of zimelidine, 20 mg/kg IP. REM latency, REM sleep, number of REM episodes, and total sleep time were significantly affected by zimelidine administration when compared t
Modifications of sleep parameters in the rat by (+)- and (-)-3-PPP
β Scribed by S.-Kafi-de St. Hilaire; J. -Y. Sovilla; S. Hjorth; J. -M. Gaillard
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 413 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1435-1463
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The administration of (-)3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP) was found to partially, but significantly, suppress the acquisition (4-8 mg/kg IP) and performance (8-16 mg/kg IP) of a conditioned avoidance response (CAR) in male Sprague-Dawley rats. All statistically significant effects we
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