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Modifications of RNA polymerase II are pivotal in regulating gene expression states

✍ Scribed by Brookes, Emily; Pombo, Ana


Book ID
109851367
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
592 KB
Volume
10
Category
Article
ISSN
1469-221X

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Regulation of Class II MHC Gene Expressi
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We have established a gene regulatory system in mice by the inducible anti-sense RNA. We have generated transgenic mice carrying the anti-sense DNA composed of the class II MHC gene under the control of the human metallothionein IIa gene promoter. The detectable amount of anti-sense RNA was constitu