𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Modification of topoisomerase genes copy number in newly diagnosed childhood acute lymphoblastic leukemia

✍ Scribed by Guérin, E; Entz-Werlé, N; Eyer, D; Pencreac'h, E; Schneider, A; Falkenrodt, A; Uettwiller, F; Babin, A; Voegeli, A-C; Lessard, M

Book ID
110055330
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
143 KB
Volume
17
Category
Article
ISSN
0887-6924

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Copy number alterations in childhood acu
Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease
✍ Doris Steinemann; Gunnar Cario; Martin Stanulla; Leonid Karawajew; Marcel Tausch 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 287 KB

## Abstract In vivo response to initial therapy, as assessed by determination of minimal residual disease (MRD) after 5 and 12 weeks of treatment, has evolved as a strong prognostic factor in children with acute lymphoblastic leukemia (ALL) treated according to the BFM regime. Individual treatment

Aberrant expression of TSC2 gene in the
Aberrant expression of TSC2 gene in the newly diagnosed acute leukemia
✍ Zhifang Xu; Min Wang; Lin Wang; Yang Wang; Xin Zhao; Qing Rao; Jianxiang Wang 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 786 KB

The tuberous sclerosis (TSC) genes, TSC1 and TSC2, encode hamartin and tuberin, respectively, and are putative tumor suppressor genes that were originally identified due to their involvement in the inherited autosomal dominant disorder tuberous sclerosis. It has been elucidated that the two proteins

Do polymorphisms in ABC transporter gene
Do polymorphisms in ABC transporter genes influence risk of childhood acute lymphoblastic leukemia?
✍ Krzysztof Jamroziak; Tadeusz Robak 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 79 KB

It is widely accepted that pathogenesis of childhood acute lymphoblastic leukemia (ALL) is related to the interplay between specific environmental exposure and inherited background. Major role of some members of the ATP-binding cassette (ABC) family of membrane transporters including MDR1 (ABCB1, P-