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Modification of release rates of cyclosporin A from polyl(L-lactic acid) microspheres by fatty acid esters and in-vivo evaluation of the microspheres

✍ Scribed by T Urata; K Arimori; M Nakano


Book ID
114163668
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
172 KB
Volume
58
Category
Article
ISSN
0168-3659

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## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable poly‐lactic‐__co__‐glycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr