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Modification of a radioimmunoassay procedure for the study of the pharmacokinetics of methotrexate in the rat

✍ Scribed by J.W. Paxton

Book ID
119085734
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
561 KB
Volume
2
Category
Article
ISSN
0160-5402

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## Abstract The pharmacokinetics and tissue distribution of methotrexate (MTX) were investigated after intravenous (i.v.) injection of free MTX (treatment I), MTX‐loaded proliposomes (treatment II), and empty proliposomes mixed manually with free MTX (treatment III), 8 mg kg^βˆ’1^, to rats using an H