## Abstract The present study was undertaken to examine the role of mitogenβactivated protein kinases (MAPKs) in apoptosis induction by phenethyl isothiocyanate (PEITC), a cruciferous vegetableβderived cancer chemopreventive agent, with DU145 and LNCaP human prostate cancer cells as a model. The MA
β¦ LIBER β¦
Modes of activation of mitogen-activated protein kinases and their roles in cepharanthine-induced apoptosis in human leukemia cells
β Scribed by Jianghong Wu; Haruhiko Suzuki; Anwarul A. Akhand; Yan-Wen Zhou; Khaled Hossain; Izumi Nakashima
- Book ID
- 114283676
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 354 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0898-6568
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## Abstract Cepharanthine (CEP) is a known membrane stabilizer that has been widely used in Japan for the treatment of several disorders such as anticancer therapyβprovoked leukopenia. We here report that apoptosis was induced by low concentrations (1β5 ΞΌM) of CEP in a human leukemia T cell line, J