Models of ARA-C chemotherapy of L1210 leukemia in mice
โ Scribed by Kenneth J. Himmelstein; Kenneth B. Bischoff
- Book ID
- 112472590
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 553 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1573-8744
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The __in vitro__ and __in vivo__ antineoplastic activity of 5โAZAโ2'โdeoxycytidine (5โAZAโCdR) and ฮฒโ2โdeoxythioguanosine (TGdR) on L1210 an L1210/ARAโC (resistant to cytosine arabinoside) leukemic cells was investigated. 5โAZAโCdR was a very potent cytotoxic agent against the L1210 leu
BDFI mice bearing L1210 leukemia were treated with chemotherapy or in combination with neuraminidase-treated cells and BCG. Histological evaluation was done on these mice at various intervals after therapy in order to determine the rate and extent of metastatic involvement in various tissues and org