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Models for α-ketoacid-dependent nonheme iron enzymes

✍ Scribed by Yu-Min Chiou; Lawrence Que Jr.


Book ID
103569256
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
65 KB
Volume
51
Category
Article
ISSN
0162-0134

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📜 SIMILAR VOLUMES


A Model for α-Keto Acid Dependent Nonhem
✍ Yu-Min Chiou; Prof. Lawrence Que Jr. 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 374 KB 👁 1 views

a-Keto acid dependent nonheme iron enzymes1'I catalyze a variety of metabolic reactions involving the functionalization of an unactivated C-H bond, concomitant with the oxidative decarboxylation of the cofactor a-keto acid. A general reaction with substrate (A) proceeds according to Equation (a).

A novel enzyme mimic for thiazolium-cata
✍ N. Bergmann; F.P. Schmidtchen 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 216 KB

The covalent combination of the thiazolium heterocycle of thiamine with macrotricyclic quaternary ammonium receptor units yields the enzyme mimics 3a,b, which show enhanced substrate selectivity and catalytic activity in decarboxylations of a-ketoacids compared to simpler salts lacking the receptor