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A Model for α-Keto Acid Dependent Nonheme Iron Enzymes: Structure and Reactivity of [Fe(Me2hdp)2(bf)](ClO4)

✍ Scribed by Yu-Min Chiou; Prof. Lawrence Que Jr.


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
374 KB
Volume
33
Category
Article
ISSN
0044-8249

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✦ Synopsis


a-Keto acid dependent nonheme iron enzymes1'I catalyze a variety of metabolic reactions involving the functionalization of an unactivated C-H bond, concomitant with the oxidative decarboxylation of the cofactor a-keto acid. A general reaction with substrate (A) proceeds according to Equation (a).