𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Models for hemoglobin and allosteric enzymes

✍ Scribed by Colin J. Thompson

Publisher
Wiley (John Wiley & Sons)
Year
1968
Tongue
English
Weight
795 KB
Volume
6
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

Synopsis

A model for hemoglobin is proposed and its application to allosteric enzymes is discussed with particular reference to asparate transcarbamylase. The main assumptions made are that the molecule is composed of subunits and that occupation of a subunit produces a conformational change which affectv the occupational probability of neighboring subunits. The results compare favorably with experiment and a number of specific predictions are made for aspartate transcarbamylase.

πŸ“œ SIMILAR VOLUMES

Time-dependent model for hemoglobin and
Time-dependent model for hemoglobin and allosteric enzymes. I. General formulation
✍ Robert Ter Bush; Colin J. Thompson πŸ“‚ Article πŸ“… 1971 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 472 KB

## Synopsis A previous equilibrium model is generalized to study time-depeiident behavior of hernoglobin aiid allosteric enzymes. An exact solution for two interacting subunits (e.g., diheme) is given, and a general method for solving the resulting set of difiereritial equations is outlined. At ha

Adipyl crosslinked bovine hemoglobins as
Adipyl crosslinked bovine hemoglobins as new models of allosteric systems
✍ Herman E. Kwansa; Alice De Young; Daniele Arosio; Anna Razynska; Enrico Bucci πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 66 KB

As indicated by peptide analyses and mass spectrometry estimations, intramolecular crosslink with bis(3,5-dibromosalicyl)adipate of bovine hemoglobin results in the formation of two main components covalently bridged across the ␀-cleft. In one component the crosslink joins the ␀ 1 V1-␀ 2 K81 residue