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Modelling the Inhibition of Amyloid-β Aggregation causing Alzheimer's Disease using D-Peptides

✍ Scribed by Olubiyi, Olujide O.; Funke, Aileen; Willbold, Dieter; Strodel, Birgit

Book ID
120497739
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
47 KB
Volume
104
Category
Article
ISSN
0006-3495

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✍ Harry Levine III 📂 Article 📅 2008 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 611 KB

## Abstract Thioflavine T (ThT) associates rapidly with aggregated fibrils of the synthetic __β__/A4‐derived peptides __β__(1–28) and __β__(1–40), giving rise to a new excitation (ex) (absorption) maximum at 450 nm and enhanced emission (em) at 482 nm, as opposed to the 385 nm (ex) and 445 nm (em)