Modeling the recurrence–progression process in bladder carcinoma
✍ Scribed by Belén García-Mora; Cristina Santamaría; Gregorio Rubio; José Luis Pontones
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 796 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0898-1221
No coin nor oath required. For personal study only.
✦ Synopsis
Wei-Lin-Weissfeld (WLW) method is used to analyze different states of the superficial vesical carcinoma distinguishing between recurrences and the possibility of progression. Two approaches are considered in this analysis to represent different aspects of the disease from a clinical point of view: the first one attempts to focus on the effect of the clinico-pathological factors on recurrences by regarding a progression before the recurrence as a censoring event, meanwhile the second one analyzes these same effects on either recurrence or progression, whichever comes first. A predictive model of recurrence or progression based on clinico-pathological factors is presented.
📜 SIMILAR VOLUMES
## Abstract ## BACKGROUND Determination of prognosis factors associated with survival, recurrence, progression, and development of metastasis in T1 and T2a transitional cell carcinoma (TCC) of the bladder is discussed. ## METHODS A study was conducted of a group of 210 patients with primary blad
We are investigating the hypothesis that cancer progression involves the formation of abnormal cadherin-catenin complexes. The detailed analysis of cadherins and catenins expressed in a panel of 17 human bladder-cancer cell lines revealed that E-cadherin was down-regulated at the mRNA level in 5 cel
## Abstract We investigated gene expression in __N__‐butyl‐__N__‐(4‐hydroxybutyl)nitrosamine (BBN)‐induced rat bladder carcinoma in order to test its applicability as a model for the study of novel therapeutic modalities, particularly gene therapy. We administered BBN in the drinking water to Wista
## Abstract ## BACKGROUND CD9 has been implicated in cell adhesion, motility, and proliferation, and numerous studies have demonstrated its prognostic value in different solid tumors. The objective of this study was to determine the relation of CD9 expression to tumor grade and tumor stage of urot