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Modeling the dynamics of the solvated SL1 domain of HIV-1 genomic RNA

✍ Scribed by G. La Penna; D. Genest; A. Perico

Publisher
Wiley (John Wiley & Sons)
Year
2003
Tongue
English
Weight
181 KB
Volume
69
Category
Article
ISSN
0006-3525

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πŸ“œ SIMILAR VOLUMES

Insight into the intrinsic flexibility o
Insight into the intrinsic flexibility of the SL1 stem-loop from genomic RNA of HIV-1 as probed by molecular dynamics simulation
✍ Sonia Mazier; Daniel Genest πŸ“‚ Article πŸ“… 2008 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 319 KB

## Abstract The SL1 stem‐loop is the dimerization initiation site for linking the two copies of the RNA forming the HIV‐1 genome. The 26 nucleotides stem contains a defect consisting on a highly conserved G‐rich 1‐3 asymmetrical internal loop, which is a major site for nucleocapsid protein binding.

On the stability of different experiment
On the stability of different experimental dimeric structures of the SL1 sequence from the genomic RNA of HIV-1 in solution: A molecular dynamics simulation and electrophoresis study
✍ S. Aci; L. Gangneux; J. Paoletti; D. Genest πŸ“‚ Article πŸ“… 2004 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 400 KB πŸ‘ 2 views

## Abstract SL1 is a stem–loop RNA sequence from the genome of HIV‐1 thought to be the initiation site for the dimerization of the retroviral genomic RNA. The aim of this study is to check the stability in solution of different experimental dimeric structures available in the literature. Two kinds