Noncovalent probes for the investigation of structure and dynamics of protein-nucleic acid assemblies: The case of NC-mediated dimerization of genomic RNA in HIV-1

On the stability of different experiment

On the stability of different experimental dimeric structures of the SL1 sequence from the genomic RNA of HIV-1 in solution: A molecular dynamics simulation and electrophoresis study

✍ S. Aci; L. Gangneux; J. Paoletti; D. Genest 📂 Article 📅 2004 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 400 KB 👁 2 views

## Abstract SL1 is a stem–loop RNA sequence from the genome of HIV‐1 thought to be the initiation site for the dimerization of the retroviral genomic RNA. The aim of this study is to check the stability in solution of different experimental dimeric structures available in the literature. Two kinds