Modeling of drug release from erodible tablets
β Scribed by Ifat Katzhendler; Amnon Hoffman; Assaf Goldberger; Michael Friedman
- Book ID
- 109388553
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 197 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
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The release of oxprenolol from drug-PMMA/MANa gel beads via the erosion process was investigated. A synchronized constant gel thickness was observed because the rates of swelling and erosion are equal, resulting in non-Fickian release kinetics. The release of oxprenolol HCl was influenced to a small
## Abstract A previously derived cubic equation describing the release of drugs from matrix tablets is compared with a more complex equation recently presented. Using data obtained from cylindrical hydrocortisone matrix tablets, it is shown that the simpler cubic equation affords an equally accepta