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Modeling huntington’s disease in cells, flies, and mice

✍ Scribed by Simonetta Sipione; Elena Cattaneo


Book ID
111640605
Publisher
Springer
Year
2001
Tongue
English
Weight
400 KB
Volume
23
Category
Article
ISSN
0893-7648

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Euploidy in somatic cells from R6/2 tran
✍ Åsa Petersén; Ylva Stewénius; Maria Björkqvist; David Gisselsson 📂 Article 📅 2005 🏛 BioMed Central 🌐 English ⚖ 556 KB

## Background Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a CAG repeat expansion in the __HD__ gene. The huntingtin protein expressed from __HD__ has an unknown function but is suggested to interact with proteins involved in the cell division machinery. The R6/2 t