## Abstract The energy of interaction is developed for three of the models applied to the action of hemoglobin. Evaluation of an energy of interaction requires a model defining the unperturbed or statistical process from which the real system is derived. The shape of a ligand binding curve by itsel
Model for the Action of Hemoglobin
โ Scribed by H. A. Saroff
- Book ID
- 123650114
- Publisher
- National Academy of Sciences
- Year
- 1970
- Tongue
- English
- Weight
- 292 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/60551
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Two loci account for all genetic variation resulting in difference in electrophoretic mobility in three hemoglobins (Hb1, Hb2, and HbX) in the hemolymph of the brine shrimp. Four alpha alleles and nine beta alleles have been studied. In shrimps of all genotypes and in electrophoresis in media with v
## Synopsis A model for hemoglobin is proposed and its application to allosteric enzymes is discussed with particular reference to asparate transcarbamylase. The main assumptions made are that the molecule is composed of subunits and that occupation of a subunit produces a conformational change wh