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Model Analysis for Oral Absorption of a Drug/Cyclodextrin Complex Involving Competitive Inclusion Complexes

✍ Scribed by Naomi Ono; Fumitoshi Hirayama; Hidetoshi Arima; Kaneto Uekama; J. Howard Rytting

Book ID
110431016
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
107 KB
Volume
44
Category
Article
ISSN
0923-0750

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✍ Mani Prabaharan; João F. Mano 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB

## Abstract **Summary:** Hydroxypropyl chitosan‐__graft__‐carboxymethyl __β__‐cyclodextrin (HPCH‐__g__‐CM __β__‐CD) was synthesized by grafting CM __β__‐CD onto HPCH using water soluble 1‐ethyl‐3‐(3‐dimethylaminopropyl)carbodiimide (EDC) as the condensing agent. Due to the presence of hydrophobic _