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Mode of Inheritance and Susceptibility Locus for Restless Legs Syndrome, on Chromosome 12q

✍ Scribed by Norman Kock; Biljana Culjkovic; Susanna Maniak; Karla Schilling; Birgitt Müller; Christine Zühlke; Laurie Ozelius; Christine Klein; Peter P. Pramstaller; Patricia L. Kramer


Book ID
117853934
Publisher
American Society of Human Genetics
Year
2002
Tongue
English
Weight
803 KB
Volume
71
Category
Article
ISSN
0002-9297

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Autosomal-dominant locus for restless le
✍ Anastasia Levchenko; Jacques-Yves Montplaisir; Géraldine Asselin; Sylvie Provost 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 308 KB 👁 1 views

## Abstract We describe an autosomal‐dominant locus for Restless Legs Syndrome (RLS) in a French‐Canadian (FC) pedigree. Genome‐wide microsatellite scan and linkage analysis were used in this study. The locus maps to chromosome 16p12.1 and spans 1.18 Mega bases. The maximum multipoint LOD scores ar