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Identification of a Major Susceptibility Locus for Restless Legs Syndrome on Chromosome 12q

โœ Scribed by Alex Desautels; Gustavo Turecki; Jacques Montplaisir; Adolfo Sequeira; Andrei Verner; Guy A. Rouleau


Book ID
117853763
Publisher
American Society of Human Genetics
Year
2001
Tongue
English
Weight
89 KB
Volume
69
Category
Article
ISSN
0002-9297

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Autosomal-dominant locus for restless le
โœ Anastasia Levchenko; Jacques-Yves Montplaisir; Gรฉraldine Asselin; Sylvie Provost ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 308 KB ๐Ÿ‘ 1 views

## Abstract We describe an autosomalโ€dominant locus for Restless Legs Syndrome (RLS) in a Frenchโ€Canadian (FC) pedigree. Genomeโ€wide microsatellite scan and linkage analysis were used in this study. The locus maps to chromosome 16p12.1 and spans 1.18 Mega bases. The maximum multipoint LOD scores ar