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Moclobemide treatment of resistant depression in a patient with vascular dementia

โœ Scribed by Yoram Barak; Hanna Suholitsky; Shlomo Noy


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
198 KB
Volume
11
Category
Article
ISSN
0885-6222

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โœฆ Synopsis


Patients suffering from dementia exhibit depressive symptoms in up to 86 per cent of cases. Syndromes meeting the criteria for major depression are more likely to respond to pharmacological therapy. Increased activity of M A 0 found in demented subjects make the treatment with MAO-inhibitors an obvious choice. Moclobemide is a novel reversible inhibitor of MAO. We describe a case of severe, resistant depression in a patient suffering from vascular dementia who responded rapidly to a low dose (150 mg/day) of moclobemide.


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