Seven patients with vascular dementia completed an 8month randomized double-blind crossover trial of bromocriptine i n a dosage of u p to 30 mg per day. Patients were assessed using a modified UCLA Parkinson Rating Scale of symptoms and signs, and neuropsychological testing including the Wechsler Ad
Moclobemide treatment of resistant depression in a patient with vascular dementia
โ Scribed by Yoram Barak; Hanna Suholitsky; Shlomo Noy
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 198 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0885-6222
No coin nor oath required. For personal study only.
โฆ Synopsis
Patients suffering from dementia exhibit depressive symptoms in up to 86 per cent of cases. Syndromes meeting the criteria for major depression are more likely to respond to pharmacological therapy. Increased activity of M A 0 found in demented subjects make the treatment with MAO-inhibitors an obvious choice. Moclobemide is a novel reversible inhibitor of MAO. We describe a case of severe, resistant depression in a patient suffering from vascular dementia who responded rapidly to a low dose (150 mg/day) of moclobemide.
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The objectives of this study were ยฎrst to compare the responses to moclobemide and sertraline in melancholic and nonmelancholic major depressive patients and secondly to compare the responses of melancholic and nonmelancholic patients in general. Sixty-three patients, with diagnosis of major depress
## Objective: Measurement of medial temporal lobe atrophy (mtl) by computerised tomography (ct) may be a useful adjunct to the diagnosis of ad. the aim of this study was to assess the sensitivity, specificity, predictive values and diagnostic accuracy of ct measurement of mtl thickness for patients