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A crossover trial of bromocriptine in the treatment of vascular dementia

✍ Scribed by Dr. Stephen E. Nadeau; Paul F. Malloy; Michael E. Andrew

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
342 KB
Volume
24
Category
Article
ISSN
0364-5134

No coin nor oath required. For personal study only.

✦ Synopsis

Seven patients with vascular dementia completed an 8month randomized double-blind crossover trial of bromocriptine i n a dosage of u p to 30 mg per day. Patients were assessed using a modified UCLA Parkinson Rating Scale of symptoms and signs, and neuropsychological testing including the Wechsler Adult Intelligence Scale-Revised, Wechsler Memory Scale, modified Thurstone Word Fluency Test, Wisconsin Card Sort, a test of visual vigilance, and a reaction time task. Subjects failed to perform significantly better on any measure while on bromocriptine, and on several measures their performance while on the drug was worse.

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