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Mn(II) binding to human serum albumin: A 1H-NMR relaxometric study

✍ Scribed by Gabriella Fanali; Yu Cao; Paolo Ascenzi; Mauro Fasano

Book ID
118037995
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
748 KB
Volume
117
Category
Article
ISSN
0162-0134

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## Abstract Mn(II) ion binds to human serum albumin (HSA) through one strong binding site (__K__~A~ = 7.9 Γ— 10^3^ M^βˆ’1^) and several weaker binding sites. Through competition assays it has been shown that the strong binding site lies in a region which has been previously identified as the Cd(II)ο£Ώ Z