## Abstract ## Background. Matrix metalloproteinases (MMPs) and transforming growth factorโฮฒ1 (TGFโฮฒ1) are important in many physiological and pathological processes. ## Methods. Immunohistochemistry for MMPโ2, MMPโ9, membraneโtype 1 MMP (MT1โMMP, MMPโ14), tissue inhibitor of matrix metalloprote
MMP-2 Protein in Invasive Breast Cancer and the Impact of MMP-2/TIMP-2 Phenotype on Overall Survival
โ Scribed by Lydia Nakopoulou; Ioanna Tsirmpa; Paraskevi Alexandrou; Androniki Louvrou; Constantine Ampela; Sophia Markaki; Panayiotis S. Davaris
- Book ID
- 110407871
- Publisher
- Springer US
- Year
- 2003
- Tongue
- English
- Weight
- 253 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Ethanol is a tumor promoter and may promote metastasis of breast cancer. However, the underlying cellular/molecular mechanisms remain unknown. Overexpression and high activity of matrix metalloproteinaseโ2 (MMPโ2) are frequently associated with metastatic breast cancers and serve as a p
## Elevated p21ras expression is associated with tumor aggressiveness in breast cancer including the extent of invasion into fat tissues, infiltration into lymphatic vessels and tumor recurrence. In the present study, we have examined the roles of H-ras and N-ras, members of the human ras gene fami