MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients
β Scribed by Langers, A M J; Verspaget, H W; Hawinkels, L J A C; Kubben, F J G M; van Duijn, W; van der Reijden, J J; Hardwick, J C H; Hommes, D W; Sier, C F M
- Book ID
- 120213782
- Publisher
- Nature Publishing Group
- Year
- 2012
- Tongue
- English
- Weight
- 232 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0007-0920
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background. Factors that represent the potential for invasion and metastasis, such as matrix metalloproteinases (MMPs), could predict prognosis of cancer. Therefore, the authors studied plasma and tissue levels of MMPβ2 and MMPβ9 in oral cancer, the leading malignancy in India. ##
Matrix metalloproteinases, and notably the gelatinases MMP-2 and MMP-9, have important roles in tumour invasion, metastasis and angiogenesis. Our study investigates the distribution of MMP-2 and MMP-9 in colorectal cancer, the correlation with plasma levels, changes following surgical resection and