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MMP-2 and MMP-9 Expression in Breast Cancer-Derived Human Fibroblasts is Differentially Regulated by Stromal-Epithelial Interactions

✍ Scribed by Christian F. Singer; Nicole Kronsteiner; Erika Marton; Marion Kubista; Kevin J. Cullen; Kora Hirtenlehner; Michael Seifert; Ernst Kubista


Book ID
110332197
Publisher
Springer US
Year
2002
Tongue
English
Weight
206 KB
Volume
72
Category
Article
ISSN
0167-6806

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## Abstract P450 aromatase catalyzes the conversion of androgens to estrogens and plays a key role in the cell growth of hormone‐dependent breast cancer in postmenopausal women. On the other hand, matrix metalloproteinases (MMPs), which can degrade almost all components of the extracellular matrix,