Frequent recurrent mutations of the human dystrophin gene lead to Duchenne and Becker muscular dystrophies. Although the approximately 2.5 Mb size of the gene may form a large target for mutations it is not clear to date which mechanisms promote the observed high frequency of spontaneous mutants (1
MLPA analysis for the detection of deletions, duplications and complex rearrangements in the dystrophin gene: potential and pitfalls
β Scribed by B. Janssen; C. Hartmann; V. Scholz; A. Jauch; J. Zschocke
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 183 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1364-6745
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