Chronic haloperidol administration incre
✍
A. John MacLennan; Stella Atmadja; Nancy Lee; H. C. Fibiger
📂
Article
📅
1988
🏛
Springer
🌐
English
⚖ 299 KB
Rats received haloperidol (1.3-1.5 mg/kg/day) via their drinking water for 21 weeks. At the end of this period the density of D2 dopamine receptors and their affinity for [3H]-spiperone were measured in the striatum and medial prefrontal cortex. The chronic haloperidol treatment increased the densit