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MK-801 and dextromethorphan block microglial activation and protect against methamphetamine-induced neurotoxicity

✍ Scribed by David M. Thomas; Donald M. Kuhn


Book ID
113500700
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
347 KB
Volume
1050
Category
Article
ISSN
0006-8993

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MK-801 protection against methamphetamin
✍ Fredric B. Weihmuller; Steven J. O'Dell; John F. Marshall πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 936 KB

Repeated administrations of methamphetamine (m-AMPH) produce high extracellular levels of dopamine (DA) and subsequent striatal DA terminal damage. Pharmacological blockade of N-methyl-D-aspartate (NMDA) receptors has been shown previously to prevent m-AMPH-induced striatal DA terminal injury, but t