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Mixed linear model approach adapted for genome-wide association studies

✍ Scribed by Zhang, Zhiwu; Ersoz, Elhan; Lai, Chao-Qiang; Todhunter, Rory J; Tiwari, Hemant K; Gore, Michael A; Bradbury, Peter J; Yu, Jianming; Arnett, Donna K; Ordovas, Jose M


Book ID
109914582
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
940 KB
Volume
42
Category
Article
ISSN
1061-4036

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## Abstract The large number of markers considered in a genome‐wide association study (GWAS) has resulted in a simplification of analyses conducted. Most studies are analyzed one marker at a time using simple tests like the trend test. Methods that account for the special features of genetic associ