Mixed Hydroxypyridinonate Ligands as Iron Chelators 1
β Scribed by Cohen, Seth M.; O'Sulliva, Brendon; Raymond, Kenneth N.
- Book ID
- 121399674
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 136 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0020-1669
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π SIMILAR VOLUMES
In a general study for developing better drugs suitable for Fe, Al, Co or lanthanide chelation therapy experiments, new mixed bisphosphonate-hydroxy pyridonates were synthesized. We demonstrate that the method using amidation reaction and dealkylation by concentrated hydrochloric acid gives excellen
## Abstract The iron(III) chelating properties of two heteropodands with 8βhydroxyquinoline and catechol binding groups were examined and compared to those of the corresponding homopodal analogues, OβTRENSOX and TRENCAMS. Like the parent homopodands, the two heteropodands are based on the TREN scaf