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Mixed germ cell sex cord–stromal tumors of the testis and ovary. Morphological, immunohistochemical, and molecular genetic study of seven cases

✍ Scribed by Michal Michal; Tomas Vanecek; Radek Sima; Petr Mukensnabl; Ondrej Hes; Dmitry V. Kazakov; Jozef Matoska; Anna Zuntova; Vladimir Dvorak; Alexander Talerman

Publisher: Springer
Year: 2006
Tongue: English
Weight: 823 KB
Volume: 448
Category: Article
ISSN: 1432-2307
DOI: 10.1007/s00428-006-0155-z

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We report the cytogenetic findings in a case of mixed germ cell-sex cord-stromal tumor of the ovary in a 5-month-old girl. Monosomy 22 was observed as the sole karyotypic abnormality. This result was confirmed by comparative genomic hybridization, which revealed no additional chromosomal imbalances.