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Mixed-effects modelling of the interspecies pharmacokinetic scaling of pegylated human erythropoietin

✍ Scribed by Koen Jolling; Juan Jose Perez Ruixo; Alex Hemeryck; An Vermeulen; Tony Greway

Book ID
113591446
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
503 KB
Volume
24
Category
Article
ISSN
0928-0987

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Differences in the disposition of certain drugs across mammalian species often arise because of their diverse physiology and anatomical characteristics. Factors such as body mass, brain weight, and maximum lifespan are related to the way that different species of mammals handle drugs. Drug dispositi