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Mitoxantrone and etoposide with or without intermediate dose cytarabine for the treatment of primary induction failure or relapsed acute myeloid leukemia

โœ Scribed by Steven M. Trifilio; Alfred W. Rademaker; Diane Newman; Katherine Coyle; Katrin Carlson-Leuer; Jayesh Mehta; Jessica Altman; Olga Frankfurt; Martin S. Tallman


Book ID
113773598
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
180 KB
Volume
36
Category
Article
ISSN
0145-2126

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Mitoxantrone, etoposide, and cytarabine
โœ Martin S. Tallman; Sandra Lee; Branimir I. Sikic; Elisabeth Paietta; Peter H. Wi ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 115 KB ๐Ÿ‘ 2 views

## Background: One potential mechanism of drug resistance to chemotherapy is the overexpression of multidrug resistance (mdr) genes coding for p-glycoprotein (p-gp), which leads to reduced intracellular retention of chemotherapy. this study tested the efficacy and toxicity of mitoxantrone, etoposid