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Single-dose mitoxantrone in combination with continuous infusion intermediate-dose cytarabine plus etoposide for treatment of refractory or early relapsed acute myeloid leukemia

✍ Scribed by Sung-Sook Lee; Je-Hwan Lee; Jung-Hee Lee; Dae-Young Kim; Se Hyung Kim; Sung-nam Lim; Young-Shin Lee; Miee Seol; Seong-Gil Ryu; Young-Ah Kang; Seongsoo Jang; Chan-Jeoung Park; Hyun-Sook Chi; Sung-Cheol Yun; Kyoo-Hyung Lee

Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 146 KB
Volume: 33
Category: Article
ISSN: 0145-2126
DOI: 10.1016/j.leukres.2008.08.009

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Pharmacology of cytarabine given as a continuous infusion followed by mitoxantrone with and without amsacrine/etoposide as reinduction chemotherapy for relapsed or refractory pediatric acute myeloid leukemia

✍ Fevzi Ozkaynak, M.; Avramis, Vassilios I.; Carcich, Sherri; Ortega, Jorge A. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB 👁 3 views

Background. The outcome of patients with acute myeloid leukemia (AML) who relapse or fail to achieve an initial remission has been dismal. Procedure. Fifteen pediatric patients with AML, 4 relapsed and 11 primary refractory, were reinduced with a loading bolus of 0.5 g/m 2 cytarabine (ara-C) followe