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Mitotic phosphorylation of Aki1 at Ser208 by cyclin B1–Cdk1 complex

✍ Scribed by Akito Nakamura; Mikihiko Naito; Hiroyuki Arai; Naoya Fujita

Book ID
116299942
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
391 KB
Volume
393
Category
Article
ISSN
0006-291X

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## Abstract Skeletal development and osteoblast maturation require the phenotype promoting activity of the transcription factor RUNX2, which controls both cell growth and differentiation in osteoblasts. We have recently shown that in actively proliferating cells RUNX2 regulates the expression of sp