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Mitogenic effects of murine serum and fibroblast growth factor on EGF nonproliferative variants of 3T3

✍ Scribed by Pruss, Rebecca M. ;Herschman, Harvey R.

Publisher
Wiley (John Wiley & Sons)
Year
1979
Tongue
English
Weight
190 KB
Volume
12
Category
Article
ISSN
0091-7419

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✦ Synopsis

Abstract

The enhanced ability of murine serum to support growth of 3T3 cells, when compared with fetal calf serum, is also evident on variants of 3T3 cells lacking the ability to bind epidermal growth factor (EGF). Variant 3T3 cell lines unable to bind EGF also retain a mitogenic response to fibroblast growth factor.

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