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Mitogenic activity of Mycoplasma pulmonis II. Studies on the biochemical nature of the mitogenic factor

✍ Scribed by Yehudith Naot; Rama Siman-Tov; Haim Ginsburg

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
624 KB
Volume
9
Category
Article
ISSN
0014-2980

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✦ Synopsis

Abstract

The mitogenic activity of Mycoplasma pulmonis has been demonstrated to reside in the membrane of this microorganism. Studies aimed at the identification of the membraneous mitogenic factor have revealed that membrane proteins are essential components of this mitogenic manifestation. In addition, it has been shown that the microorganism's outer surface membrane proteins are responsible for mitogenic activity. It has been shown, however, that isolated membrane lipids are not mitogenic for rat lymphocytes and are not required for the membrane's mitogenic potential.

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