## Abstract We have examined the effects of colchicine on concanavalin A (Con A)‐ and phytohemagglutinin (PHA)‐stimulated human peripheral blood lymphocytes and from the time course of proliferation have extracted the relative size of the responding cell population, the rate of entry of this popula
In vitro studies on the release of mitogenic factor by sensitized human lymphocytes
✍ Scribed by K. Havemann; S. Bürger
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 615 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
✦ Synopsis
Release of mitogenic factor by sensitized lymphocytes 285
Other studies have shown that humoral antibodies are capable to induce lymphocyte cytotoxicity in strictly allogeneic or autoimmune models [15, 161. MacLennan et al.
[30] have also presented evidence that human antibodies of IgG class may induce human blood lymphocytes to become cytotoxic to tissue culture cells of human origin. Cobncoated CRBC should therefore be suitable target cells for further studies of interactions between lymphocytes and antibodies t o colon in human ulcerative colitis.
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