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Mitogen-induced initiation of DNA synthesis by lymphocytes cultured in serum-free media

✍ Scribed by Wei Li; Rakesh K. Kumar


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
81 KB
Volume
23
Category
Article
ISSN
0165-2478

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The effect of sodium orthovanadate on enhancement of DNA synthesis by T and B cell mitogenic agents was studied using murine thymocytes and splenocytes. Addition of vanadate to thymocyte cultures inhibited the mitogenic response induced by concanavalin A in a dose dependent manner (50% inhibition at