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In vivo enhancement of mitogen-induced lymphocyte DNA synthesis by sodium diethyl-dithiocarbamate (DTC)

โœ Scribed by P.J. Neveu; D. Perdoux; L. Lafleur


Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
293 KB
Volume
4
Category
Article
ISSN
0192-0561

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โœ M. Ramanadham; Milton Kern ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer ๐ŸŒ English โš– 365 KB

The effect of sodium orthovanadate on enhancement of DNA synthesis by T and B cell mitogenic agents was studied using murine thymocytes and splenocytes. Addition of vanadate to thymocyte cultures inhibited the mitogenic response induced by concanavalin A in a dose dependent manner (50% inhibition at