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Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle

✍ Scribed by D. Williamson; P. Gallagher; M. Harber; C. Hollon; S. Trappe


Book ID
111120157
Publisher
Cambridge University Press
Year
2003
Tongue
English
Weight
989 KB
Volume
547
Category
Article
ISSN
0022-3751

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Multiple studies demonstrate that manganese (Mn) exposure potentiates inflammatory mediator output from activated glia; this increased output is associated with enhanced mitogen activated protein kinase (MAPK: p38, ERK and JNK) activity. We hypothesized that Mn activates MAPK by activating the kinas