Manganese modulation of MAPK pathways: e
โ
Patrick L. Crittenden; Nikolay M. Filipov
๐
Article
๐
2010
๐
John Wiley and Sons
๐
English
โ 712 KB
Multiple studies demonstrate that manganese (Mn) exposure potentiates inflammatory mediator output from activated glia; this increased output is associated with enhanced mitogen activated protein kinase (MAPK: p38, ERK and JNK) activity. We hypothesized that Mn activates MAPK by activating the kinas