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Mitogen activated protein kinase (MAPK) mediates non-genomic pathway of estrogen on T cell cytokine production following trauma-hemorrhage

✍ Scribed by Takao Suzuki; Huang-Ping Yu; Ya-Ching Hsieh; Mashkoor A. Choudhry; Kirby I. Bland; Irshad H. Chaudry


Book ID
116398171
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
249 KB
Volume
42
Category
Article
ISSN
1043-4666

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Estrogen-mediated activation of non-geno
✍ Takao Suzuki; Huang-Ping Yu; Ya-Ching Hsieh; Mashkoor A. Choudhry; Kirby I. Blan 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 356 KB

## Abstract Although 17β‐estradiol (E2) attenuates the alterations in Kupffer cells and splenic macrophages (MΦ) cytokine production following trauma‐hemorrhage, the mechanism by which this occurs remains unknown. Utilizing a cell‐impermeable E2 conjugated with BSA (E2‐BSA), we examined the non‐gen