Mitochondrial translocator protein modulates metabolism and pharmacologically induced apoptosis in breast cancer cells
β Scribed by A Gastaldello, P Gami, H Callaghan, M Campanella
- Book ID
- 120699697
- Publisher
- BioMed Central
- Year
- 2010
- Tongue
- English
- Weight
- 390 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1465-5411
- DOI
- 10.1186/bcr2536
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## Abstract This report describes that protein kinase C delta (PKCΞ΄) overexpression prevents TRAILβinduced apoptosis in breast tumor cells; however, the regulatory mechanism(s) involved in this phenomenon is(are) incompletely understood. In this study, we have shown that TRAILβinduced apoptosis was