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Mitochondrial RNA Processing and Translation: Link between Mitochondrial Mutations and Hearing Loss?

✍ Scribed by Nathan Fischel-Ghodsian


Book ID
115639437
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
75 KB
Volume
65
Category
Article
ISSN
1096-7192

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Some cases of maternally inherited isolated deafness are caused by mtDNA mutations, frequently following an exposure to aminoglycosides. Two mitochondrial genes have been clearly described as being affected by mutations responsible for this pathology: the ribosomal RNA 12S gene and the transfer RNA