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Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants

✍ Scribed by Ana Navarro; Alberto Boveris


Book ID
113418271
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
814 KB
Volume
60
Category
Article
ISSN
0169-409X

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Brain mitochondrial dysfunction in aging
✍ Alberto Boveris; Ana Navarro πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 178 KB

## Abstract Aging of mammalian brain is associated with a continuous decrease of the capacity to produce ATP by oxidative phosphorylation. The impairment of mitochondrial function is mainly due to diminished electron transfer by complexes I and IV, whereas inner membrane H^+^ impermeability and F~1