Mitochondrial matters of the brain: mitochondrial dysfunction and oxidative status in epilepsy
β Scribed by Sue -Joan Chang; Bu-Chin Yu
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 85 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0145-479X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Increasing evidence supports the notion that increased oxidative stress is a fundamental cause in the aging process and in neurodegenerative diseases. As a result, a decline in cognitive function is generally associated with brain aging. Reactive oxygen species (ROS) are highly reactive
To screen fibroblasts for defects in lactate/pyruvate oxidation, cells were grown to confluence in \(25-\mathrm{cm}^{2}\) flasks, rinsed, and incubated in glucose-free media containing \(25 \mu \mathrm{M}\) L-lactate and \(0.1 \mu \mathrm{Ci}\left[\mathrm{D}, \mathrm{L}-1-{ }^{14} \mathrm{C}\right]\