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Mitochondrial matters of the brain: amyloid formation and Alzheimer’s disease introduction

✍ Scribed by Peter L. Pedersen


Publisher
Springer US
Year
2009
Tongue
English
Weight
136 KB
Volume
41
Category
Article
ISSN
0145-479X

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## Abstract Proteolytic processing of the amyloid precursor protein by β ‐and γ‐secretases results in the production of Alzheimer's disease (AD) Aβ amyloid peptides. Modulation of secretase activity is being investigated as a potential therapeutic approach. Recent studies with human brain have reve