Polymorphic variation of the human mitochondrial malic enzyme was detected in Caucasians and Negroes. The frequencies of the two alleles determining the three mitochondrial malic enzyme phenotypes were 0.69 and 0.31 in the Caucasian sample and 0.82 and 0.18 in the much smaller Negro sample. The dist
Mitochondrial malic enzyme polymorphism in Japanese population
β Scribed by Kazue Abe; Katsunori Akiyama
- Publisher
- Nature Publishing Group
- Year
- 1983
- Tongue
- English
- Weight
- 331 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1435-232X
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π SIMILAR VOLUMES
Mitochondrial malic enzyme MEM (E.C. 1.1.1.40) is present in human leukocytes; the polymorphism of MEM thus can be easily demonstrated using routine starch gel electrophoresis. Data on formal genetics are given. The gene frequency of MEM1 was estimated to be 0.67 +/- 0.02.
The question was investigated whether mitochondria in the mammalian skeletal muscle fiber syncytium ineorporate gene products encoded by one or many nuclei. Mouse chimeras were produced from strains which differ in their electrophoretic variants of the nuclear-coded mitochondrial protein, malic enzy